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Cambourne, Cambridgeshire Langton Howarth Ltd
Location: Site based in Pampisford, Cambridgeshire

This role is available as either full time Monday - Friday or part time (30 hours per week/4 days a week)

Our client is a leading integrated drug discovery CRO that has been setting the highest standards in drug discovery, with a particular emphasis on small molecule research, since the early 2000s.

They work in partnership with clients from a variety of sectors including academic, pharmaceutical, biotechnology and patient foundation organisations around the world with a focus on Assay Biology, Bespoke Assay Development, Small Molecules. Working across all disease areas you will have the opportunity to broaden your experience and skillset, by managing a range of bespoke assay development projects.

The role of Associate Principle Scientist:

Plan and implement experimental protein production or structural biology projects, solving any problems that arise
Undertake protein expression (E. coli, insect and/or mammalian), expression optimisation, protein purification optimisation and scale up to multi mg scale for structural analysis, protein QC, protein-ligand crystallisation
Managing client projects
Support routine laboratory operation and maintenance
Prepare and present oral and written reports on research activities to internal and external audiences
Actively pursue own personal development
Maintain appropriate awareness of safety procedures, attend required safety training and adhere to laboratory safety rules as defined by the host department
Ensure that all duties are performed in accordance with organisational standards, policies, and procedures
The requirements of the Associate Principle Scientist:

To be considered for this exciting role you will already have 5+ years of experience post education as an Associate Principal Scientist or Principal Scientist in the protein science/structural biology field
You will have gained this experience working for either a CRO, Pharmaceutical or Biotech company & ideally in a small molecule drug discovery environment
You will be able to work independently in protein expression (E.coli, insect and/or mammalian), expression optimisation, protein purification optimisation and scale up to multi mg scale for structural analysis, protein QC and protein-ligand crystallisation
You will have demonstratable experience using a range of AKTA chromatography equipment and columns
Experience in crystal manipulation/ freezing, solving protein-ligand X-ray crystal structures independently would be a plus
Ideally you will have a PhD in a protein based area such as Biochemisty, Protein Science, Molecular Biology or related areas (BSc/MSc degree candidates are also welcomed to apply with relevant industry experience
The successful candidate will be enthusiastic, a quick learner, have good problem-solving skills, and be able to work effectively in an inter-disciplinary team
Salary & Benefits:

Base Salary Circa £40,000 - £60,000 DOE
Pension (10% employer contribution & 5% employee)
Private Medical Cover
4 x salary life insurance
25 days holiday + 8 Bank Holidays
Free Parking Onsite
To be considered for this role you must have a full right to work in the UK

Langton Howarth also operates a recommend a friend referral scheme. So, if you know someone who could be good for this job, email your nominated candidates name and contact details in confidence and well ensure you receive £100.00(o/e) of vouchers from a high street retailer of your choice.
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